and Design in Biological Chemistry and Biophysics

Protein-protein interactions in paralogues: Electrostatics modulates specificity on a conserved steric scaffold

An improved knowledge of protein-protein interactions is essential for better understanding of metabolic and signaling networks, and cellular function. Progress tends to be based on structure determination and predictions using known structures, along with computational methods based on evolutionary information or detailed atomistic descriptions.

type: 
Journal Paper
journal: 
PLOS ONE, 10 Oct 2017, doi: 10.1371/journal.pone.018592
pubmed: 
29016650
Url: 
https://www.ncbi.nlm.nih.gov/pubmed/29016650
Impact Factor: 
2.806
Date of acceptance: 
2017-12-27
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