NOOKAEW Intawat

Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons

The stochastic dynamics and regulatory mechanisms that govern differentiation of individual human neural precursor cells (NPC) into mature neurons are currently not fully understood. Here, we used single-cell RNA-sequencing (scRNA-seq) of developing neurons to dissect/identify NPC subtypes and critical developmental stages of alternative lineage specifications.

type: 
Journal Paper
journal: 
Genome Research 2017, 27, Pg 1783-1794, doi: 10.1101/gr.223313.117
pubmed: 
29030469
Url: 
http://genome.cshlp.org/content/27/11/1783.long
Impact Factor: 
11.922
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