The next step in systems biology: simulating the temporospatial dynamics of molecular network

Published date : 29 Dec 2003

As a result of the time- and context-dependency of gene expression, gene regulatory and signaling pathways undergo dynamic changes during development. Creating a model of the dynamics of molecular interaction networks offers enormous potential for understanding how a genome orchestrates the developmental processes of an organism. The dynamic nature of pathway topology calls for new modeling strategies that can capture transient molecular links at the runtime.

Journal Paper
BioEssays Vol (2004), 68-72
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