Optimal Charge-to-Spin Conversion in Graphene on Transition-Metal Dichalcogenides

Published date : 07 Nov 2017

When graphene is placed on a monolayer of semiconducting transition metal dichalcogenide (TMD) its band structure develops rich spin textures due to proximity spin-orbital effects with interfacial breaking of inversion symmetry. In this work, we show that the characteristic spin winding of low-energy states in graphene on a TMD monolayer enables current-driven spin polarization, a phenomenon known as the inverse spin galvanic effect (ISGE).

type
Journal Paper
journal
Physical Review Letters, Vol. 114, Issue 119, 10 Nov 2017, doi: 10.1103/PhysRevLett.119.196801
Impact Factor
8.462

High-throughput Prediction of Nephrotoxicity in Humans

Published date : 05 Nov 2017

The Lush Science Prize 2016 was awarded to Daniele Zink and Lit-Hsin Loo for the interdisciplinary
and collaborative work between their research groups in developing alternative methods for the
prediction of nephrotoxicity in humans. The collaboration has led to the establishment of a series of pioneering alternative methods for nephrotoxicity prediction, which includes: predictive gene expression
markers based on pro-inflammatory responses; predictive in vitro cellular models based on pluripotent

type
Journal Paper
journal
ATLA 45, Pg 241-252, 5 Nov 2017
Impact Factor
1.021

APD volumetric app: android app for the quantification of reagents

Published date : 03 Nov 2017

Quantifying reagents is a necessity in laboratory experiment planning but to do so with reasonable accuracy is a challenge when using unmarked containers. While there are volumetric measuring cylinders, the demand of sterility and purity in many experiments prevent their use in a feasible fashion. As a result, experienced estimation is usually relied upon, but this is fairly subjective, and may lead to large margins of error.

type
Journal Paper
journal
Scientific Phone Apps and Mobile Devices (2017) 3:7, doi: 10.1186/s41070-017-0019-8

Inter-Species Host Gene Expression Differences in Response to Human and Avian Influenza A Virus Strains

Published date : 01 Nov 2017

Low pathogenic avian influenza (LPAI) viruses are a source of sporadic human infections and could also contribute to future pandemic outbreaks but little is known about inter-species differences in the host responses to these viruses. Here, we studied host gene expression signatures of cell lines from three species (human, chicken, and canine) in response to six different viruses (H1N1/WSN, H5N2/F59, H5N2/F118, H5N2/F189, H5N3 and H9N2).

type
Journal Paper
journal
International Journal of Molecular Sciences, Vol. 18, Issue 11, doi: 10.3390/ijms18112295
Impact Factor
3.226

Multiview and Multimodal Pervasive Indoor Localization

Published date : 23 Oct 2017

Pervasive indoor localization (PIL) aims to locate an indoor mobile-phone user without any infrastructure assistance. Conventional PIL approaches employ a single probe (i.e., target) measurement to localize by identifying its best match out of a fingerprint gallery. However, a single measurement usually captures limited and inadequate location features. More importantly, the reliance on a single measurement bears the inherent risk of being inaccurate and unreliable, due to the fact that the measurement could be noisy and even corrupted.

type
Conference Paper/Poster
journal
Multi Media 17, Proceedings of the 2017 ACM on Multimedia Conference, Pg 109-117. Mountain view, California, USA, Oct 23-27 2017, doi: 10.1145/3123266.3123436

Multiview and Multimodal Pervasive Indoor Localization

Published date : 23 Oct 2017

Pervasive indoor localization (PIL) aims to locate an indoor mobile-phone user without any infrastructure assistance. Conventional PIL approaches employ a single probe (i.e., target) measurement to localize by identifying its best match out of a fingerprint gallery. However, a single measurement usually captures limited and inadequate location features. More importantly, the reliance on a single measurement bears the inherent risk of being inaccurate and unreliable, due to the fact that the measurement could be noisy and even corrupted.

type
Conference Paper/Poster
journal
"Multi Media 17, Proceedings of the 2017 ACM on Multimedia Conference, Pg 109-117. Mountain view, California, USA, Oct 23-27 2017, doi: 10.1145/3123266.3123436 "

A New Generation of Arachidonic Acid Analogues as Potential Neurological Agent Targeting Cytosolic Phospholipase A2

Published date : 20 Oct 2017

Cytosolic phospholipase A2 (cPLA2) is an enzyme that releases arachidonic acid (AA) for the synthesis of eicosanoids and lysophospholipids which play critical roles in the initiation and modulation of oxidative stress and neuroinflammation. In the central nervous system, cPLA2 activation is implicated in the pathogenesis of various neurodegenerative diseases that involves neuroinflammation, thus making it an important pharmacological target. In this paper, a new class of arachidonic acid (AA) analogues was synthesized and evaluated for their ability to inhibit cPLA2.

type
Journal Paper
journal
Scientific Reports 7, Article no: 13684, 2017, doi:10.1038/s41598-017-13996-8
Impact Factor
4.259

Protein-protein interactions in paralogues: Electrostatics modulates specificity on a conserved steric scaffold

Published date : 17 Oct 2017

An improved knowledge of protein-protein interactions is essential for better understanding of metabolic and signaling networks, and cellular function. Progress tends to be based on structure determination and predictions using known structures, along with computational methods based on evolutionary information or detailed atomistic descriptions.

type
Journal Paper
journal
PLOS ONE, 10 Oct 2017, doi: 10.1371/journal.pone.018592
Impact Factor
2.806

Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons

Published date : 13 Oct 2017

The stochastic dynamics and regulatory mechanisms that govern differentiation of individual human neural precursor cells (NPC) into mature neurons are currently not fully understood. Here, we used single-cell RNA-sequencing (scRNA-seq) of developing neurons to dissect/identify NPC subtypes and critical developmental stages of alternative lineage specifications.

type
Journal Paper
journal
Genome Research 2017, 27, Pg 1783-1794, doi: 10.1101/gr.223313.117
Impact Factor
11.922