Translational Research Division

Application Notes on APD Areametric App: Automated area quantification for both Android and iOS

Published date : 08 Feb 2019

Area measurements have a wide range of uses from the monitoring of skin features in healthcare, celestial bodies in astronomy, to determining furniture sizes in everyday indoor uses. Current measurement methods utilize some form of measuring tool and unless performed by skilled and trained professionals, human errors leading to inaccurate measurements can often arise. This is especially so for irregularly shaped objects with complex dimensions.

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Journal Paper
journal
APD Trove 2019, Vol: 2;1, doi: 10.30943/2019/08022019

A Review of Apps for Programming: programming languages and making apps with apps

Published date : 26 Jan 2019

With the latest technologies enabling smartphones to work like mini computers, there are now numerous opportunities to use smartphones for the development of mobile apps. Given the multiple Operating Systems (OS) available, there is a significant demand for apps for the various platforms. To meet this demand, some apps exist to impart the necessary knowledge to make apps, while others make the programming of apps possible on these devices. Surveying both the Google Play and Apple App stores, there are a plethora of such programming apps, classified based on the various languages.

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Journal Paper
journal
Scientific Phone Apps and Mobile Devices (2019) 5:1, doi:10.30943/2019/25012019

Perspective: The promises of a holistic view of proteins-impact on antibody engineering and drug discovery

Published date : 10 Jan 2019

The reductionist approach is prevalent in biomedical science. However, increasing evidence now shows that biological systems cannot be simply considered as the sum of its parts. With experimental, technological and computational advances, we can now do more than view parts in isolation, thus wepropose that an increasing holistic view (where a protein is investigated as much as a whole as possible) is now timely. To further advocate this, we review and discuss several studies and applications involving allostery,where distant protein regions can cross-talk to influence functionality.

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Journal Paper
journal
Bioscience Reports, Jan 10, 2019, DOI: 10.1042/BSR20181958
Impact Factor
2.899

Lipid accumulation facilitates mitotic slippage-induced adaptation to anti-mitotic drug treatment

Published date : 27 Nov 2018

Aberrant lipid accumulation is a hallmark of cancer known to contribute to its aggressiveness and malignancy. Emerging studies have demonstrated context-dependent changes in lipid metabolism during chemotherapy. However, there is little known regarding the mechanisms linking lipid metabolism to chemotherapy-induced cell fates. Here, we describe lipid accumulation in cells following antimitotic drug treatment. Cells arrested in mitosis, as well as cells that escaped mitotic arrest and underwent mitotic slippage, showed elevated cytoplasmic lipid droplets.

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Journal Paper
journal
Cell Death Discovery 4, Article no: 109. 2018, doi: 10.1038/s41420-018-0127-5

Commentary: Augmented Reality Scientific Phone Apps - making the APD AR Holistic Review app and using existing AR apps for scientific publications

Published date : 02 Oct 2018

The average scientific publication is not the most palatable of reading materials, especially to those not in the relevant disciplines. Yet, conveying scientific concepts easily is precisely what scientific publications are meant to do. Imagine what the use of video pictures/paintings as depicted in the Harry Potter movie series can do to make things easier! While the fantasy of moving photos/pictures does not exist physically in the real world, just as Santa Claus cannot travel the world today without being shot down by anti-missiles, there are some shadows of reality in this idea.

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Journal Paper
journal
Scientific Phone Apps and Mobile Devices (2018) 4:4, doi:10.30943/2018/28092018

Editorial : A New Home for "Scientific Phone Apps and Mobile Devices" Journal

Published date : 28 Sep 2018

The original intent of academic publication to disseminate information and findings to the community for scientific progress has taken different twists and turns particularly in the last few decades. With the Internet, there is now the option of E-publications, and more recently, open access publishing to make articles freely available to readers. No longer are the articles restricted to subscribing academics, but now also to the general public.

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Journal Paper
journal
Scientific Phone Apps and Mobile Devices (2018) 4:3, doi: 10.30943/2018/26042018

The Associations between Dietary Practices and Dietary Quality, Biological Health Indicators, Perceived Stress, Religiosity, Culture, and Gender in Multi-Cultural Singapore

Published date : 29 Jul 2018

Dietary quality, biological health, culture, religiosity, and perceived stress are co-related. However, there is a dearth of research conducted on Asian populations in secularized and harmonious multi-cultural societies. This study addresses these gaps by conducting an investigation in the multi-cultural and multi-religious Singapore to examine the parameters of culture and gender and the associations with 1) dietary quality, 2) biological health indicators, 3) religiosity, and perceived stress.

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Journal Paper
journal
Journal of Ethnic Foods, 2018, doi: 10.1016/j.jef.2018.07.003

Potent tocolytic activity of ethyl acetate fraction of Ananas comosus on rat and human uteri

Published date : 18 Jun 2018

The aim of this study was to investigate the tocolytic properties of Ananas comosus extract in rat and human uterine tissue in vitro and in the rat in vivo. Organ bath technique was employed to perform functional studies in vitro. The PhysioTel transmitter was implanted in SD rats to measure the changes in intrauterine pressure (IUP) in vivo. Analyses of F2 was performed using LC-HRMS.

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Journal Paper
journal
Biomedicine & Pharmacotheraphy, Vol. 105, Sept 2018, Pg 824-834, doi: 10.1016/j.biopha.2018.06.021
Impact Factor
2.759