Tan Chew Lim

Gland segmentation in prostatehistopathological images

Published date : 21 Jun 2017

Glandular structural features are important for the tumor pathologist in the assessment of cancer malignancy of prostate tissue slides. The varying shapes and sizes of glands combined with the tedious manual observation task can result in inaccurate assessment. There are also discrepancies and low-level agreement among pathologists, especially in cases of Gleason pattern 3 and pattern 4 prostate adenocarcinoma. An automated gland segmentation system can highlight various glandular shapes and structures for further analysis by the pathologist.

type
Journal Paper
journal
Journal of Medical Imaging, 2017 Apr;4(2):027501, doi: 10.1117/1.JMI.4.2.027501

Unsupervised medical image classification by combining case-based classifiers

Published date : 01 Aug 2013

We introduce an automated pathology classification system for medical volumetric brain image slices. Existing work often relies on handcrafted features extracted from automatic image segmentation. This is not only a challenging and time-consuming process, but it may also limit the adaptability and robustness of the system. We propose a novel approach to combine sparse Gabor-feature based classifiers in an ensemble classification framework. The unsupervised nature of this non-parametric technique can significantly reduce the time and effort for system calibration.

type
Conference Paper/Poster
journal
In Proceedings of the 14th World Congress on Health and Biomedical Informatics (MEDINFO 2013), Copenhagen, Denmark, Aug 2013