Haw Yu Xuan

Structural analyses of 2015-updated drugresistant mutations in HIV-1 protease: an implication of protease inhibitor crossresistance

Published date : 16 Dec 2016

Background: Strategies to control HIV for improving the quality of patient lives have been aided by the Highly Active Anti-Retroviral Therapy (HAART), which consists of a cocktail of inhibitors targeting key viral enzymes. Numerous new drugs have been developed over the past few decades but viral resistances to these drugs in the targeted viral enzymes are increasingly reported. Nonetheless the acquired mutations often reduce viral fitness and infectivity.

type
Journal Paper
journal
BMC Bioinformatics 2016, 17(Suppl 19):500 doi: 10.1186/s12859-016-1372-3
Impact Factor
2.435

An overview of clinically and healthcare related apps in Google and Apple app stores: connecting patients, drugs, and clinicians

Published date : 19 Jul 2016

Successful clinical outcomes involve both clinician and patient factors such as good decision making, accurate diagnosis, patient compliance, effective monitoring of the condition, and accurate interpretation of clinical results. With a general trend in healthcare towards personalized medicine, the smartphone holds great potential to play a role in personalized care and aid in the above mentioned factors. Through the use of apps, the increasingly powerful smartphone may be a useful aid in the healthcare and clinical industries.

type
Journal Paper
journal
Scientific Phone Apps and Mobile Devices 2016 2:8 DOI: 10.1186/s41070-016-0012-7

The relaxation effects of stimulative and sedative music on mathematics anxiety: A perception to physiology model

Published date : 19 Jun 2015

Previous research on music and mathematics anxiety has relied primarily on self-reports without biological measurements. To address whether these parameters were correlated, we included blood pressure physiological measures, the State-Trait Anxiety Inventory (STAI) and the Mathematics Anxiety Rating Scale (MARS) in our study. One hundred and five psychology undergraduates were assigned to sedative, stimulative and “no music” conditions while completing Cambridge GCE O Level mathematical questions. Anxiety was measured pre-, during and posttest.

type
Journal Paper
journal
Psychology of Music 2015, Pg. 1 - 12, doi:10.1177/0305735615590430
Impact Factor
1.903