Bu Wenyu

Detection and Quantitative Measurement of Neuronal Outgrowth in Fluorescence Microscopy Images

Published date : 14 Jul 2009
type
Conference Paper/Poster
journal
Medical Image Understanding and Analysis (MIUA) 2009, 14-15 July 2009, Kingston University, London
Impact Factor
NIL

Quantitative Neurite Outgrowth Measurement Based on Image Segmentation with Topological Dependece

Published date : 24 Oct 2008

The study of neuronal morphology and neurite outgrowth has been enhanced by the combination of imaging informatics and high content screening, in which thousands of images are acquired using robotic fluorescent microscopy. To understand the process of neurite outgrowth in the context of neuroregeneration, we used mouse neuroblastoma N1E115 as our model neuronal cell. Six-thousand cellular images of four different culture conditions were acquired with two-channel widefield fluorescent microscopy. We developed a software package called NeuronCyto.

type
Journal Paper
journal
Cytometry Part A, 75A: Pg 289-297, 2009, ISSN: 1552-4930, doi: 10.1002/cyto.a.20664
Impact Factor
2.978