FENG lin

FMAj: a tool for high content analysis of muscle dynamics in Drosophila metamorphosis

Published date : 08 Dec 2014

Background
During metamorphosis in Drosophila melanogaster, larval muscles undergo two different developmental fates; one population is removed by cell death, while the other persistent subset undergoes morphological remodeling and survives to adulthood. Thanks to the ability to perform live imaging of muscle development in transparent pupae and the power of genetics, metamorphosis in Drosophila can be used as a model to study the regulation of skeletal muscle mass. However, time-lapse microscopy generates sizeable image data that require new tools for high throughput image analysis.

type
Journal Paper
journal
BMC Bioinformatics201415(Suppl 16):S6, doi: 10.1186/1471-2105-15-S16-S6
Impact Factor
2.435