NAIR Vrundha M

Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing

Published date : 05 Nov 2013

Exosomes are nanosized (30-100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes. Because exosomes have been isolated from most body fluids they may provide a source for non-invasive cancer diagnostics.

Journal Paper
PeerJ. 2013 Nov 5,