Kimber I

Proteomic and bioinformatic analyses for the identification of proteins with low allergenic potential for hazard assessment

Published date : 23 Mar 2019

Use of botanicals and natural substances in consumer products has increased in recent years. Such extracts can contain protein that may theoretically represent a potential risk of IgE-mediated allergy. No method has yet been generally accepted or validated for assessment of the allergenic potential of proteins. For development of suitable methods datasets of allergenic and non-allergenic (or low allergenic) proteins are required that can serve, respectively, as positive and negative controls. However, data are unavailable on proteins that lack or have low allergenic potential.

Journal Paper
Toxicological Sciences, 2019 Mar 23. pii: kfz078. doi: 10.1093/toxsci/kfz078.
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