Al-Mubaarak A

A bio-functional polymer that prevents retinal scarring through modulation of NRF2 signalling pathway

Aberrant wound healing, which leads to irreversible fibrosis, underpins many pathological diseases. In the eye, this manifests as proliferative vitreoretinopathy (PVR), a major cause of poor vision due to failed retinal detachment (RD) surgery1,2. PVR occurs due to proliferative and contractile fibrocellular scar membranes that form either in the vitreous or surrounding the retina.