Alfatah et al. interrogate the relationship between glucose metabolism and TORC1 activation in Saccharomyces cerevisiae. They identify three distinct pathways for glucose-induced TORC1 activation, with each pathway requiring a different extent of glucose metabolism via the glycolytic pathway.
ReadPhthalate esters (PAE) are compounds derived by double esterification of phthalic acid (1,2-benzenedicarboxylic acid). Since the Industrial Revolution, low molecular weight phthalates such as dimethyl phthalate (DMP) and diethyl phthalate (DEP) have been used in pharmaceutical and manufacturing industries to confer flexibility to products used in personal care, infant care and medical devices1.
ReadIncreased risk of SARS-CoV-2 Delta acquisition compared with other variants was reduced with vaccination. Close-contacts of vaccinated Delta-infected indexes did not have statistically significant reduced risk of acquisition compared with unvaccinated Delta-infected indexes.
ReadBackground he impact of SARS-CoV-2 variants of concern (VOCs) on disease severity is unclear. In this retrospective study, we compared outcomes of patients infected with B.1.1.7, B.1.351, and B.1.617.2 with those with wild-type strains from early 2020.
ReadBACKGROUND: Three clusters of coronavirus disease 2019 (COVID-19) linked to a tour group from China, a company conference, and a church were identified in Singapore in February, 2020. METHODS: We gathered epidemiological and clinical data from individuals with confirmed COVID-19, via interviews and inpatient medical records, and we did field investigations to assess interactions and possible modes of transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Open source reports were obtained for overseas cases. We reported the median (IQR) incubation period of SARS-CoV-2.
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