Bioinformatics Institute

Bioinformatics Institute

Repository of all published Science Articles by our Researchers, their Group Members and Collaborators.

Bioinformatics Institute
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    Heng E

    Identification and engineering of 32 membered antifungal macrolactone notonesomycins

    Notonesomycin A is a 32-membered bioactive glycosylated macrolactone known to be produced by Streptomyces aminophilus subsp. notonesogenes 647-AV1 and S. aminophilus DSM 40186. In a high throughput antifungal screening campaign, we identified an alternative notonesomycin A producing strain, Streptomyces sp. A793, and its biosynthetic gene cluster.

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