Leong KP
The Singapore National Precision Medicine Strategy
Precision medicine promises to transform healthcare for groups and individuals through early disease detection, refining diagnoses and tailoring treatments. Analysis of large-scale genomic-phenotypic databases is a critical enabler of precision medicine.
ReadA five-safes approach to a secure and scalable genomics data repository
Genomics, Data encryption, Data storage representation
ReadLarge-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore
Underrepresentation of Asian genomes has hindered population and medical genetics research on Asians, leading to population disparities in precision medicine. By whole-genome sequencing of 4,810 Singapore Chinese, Malays, and Indians, we found 98.3 million SNPs and small insertions or deletions, over half of which are novel.
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