MacAry P
SARS-CoV-2 spike protein as a bacterial lipopolysaccharide delivery system in an overzealous inflammatory cascade
Keywords: COVID-19, SARS-CoV-2, spike protein, lipopolysaccharide, TLR4, hyperinflammation
ReadSARS-CoV-2 spike protein as a bacterial lipopolysaccharide delivery system in an overzealous inflammatory cascade
Pulmonary and systemic hyperinflammation are some of the prominent hallmarks of severe COVID-19 disease.
ReadUncovering cryptic pockets in the SARS-CoV-2 spike glycoprotein
The COVID-19 pandemic has prompted a rapid response in vaccine and drug development. Herein, we modeled a complete membrane-embedded SARS-CoV-2 spike glycoprotein and used molecular dynamics simulations with benzene probes designed to enhance discovery of cryptic pockets.
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