Patel S

A novel 3-miRNA network regulates tumour progression in oral squamous cell carcinoma

This study identified potential salivary exosome-derived miRNA biomarkers and crucial miRNA-mRNA networks/underlying mechanisms responsible for OSCC progression.

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Salivary Exosomal miRNA-1307-5p Predicts Disease Aggressiveness and Poor Prognosis in Oral Squamous Cell Carcinoma Patients

Keywords: oral cancer; exosomes; saliva; microRNAs; prognosis; chemoresistance

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Saliva Based Liquid Biopsies in Head and Neck Cancer: How Far Are We From the Clinic?

Head and Neck Cancer (HNC) is the sixth most prevalent cancer worldwide attributed to etiological factors like tobacco and alcohol consumption, HPV infections and to a certain extent genetic predisposition (1–3). Despite advancements in diagnostic and therapeutic regime, the overall survival of HNC patients has remained dismal for over four decades.

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Saliva Based Liquid Biopsies in Head and Neck Cancer: How Far Are We From the Clinic?

Keywords: biomarker; circulating tumor nucleic acids; extracellular vesicles; head and neck cancer; liquid biopsy; metabolomics; saliva.

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