Patridge A

Molecular descriptors suggest stapling as a strategy for optimizing membrane permeability of cyclic peptides

Cyclic peptides represent a promising class of drug candidates. A significant obstacle limiting their development as therapeutics is the lack of an ability to predict their membrane permeability.

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Molecular descriptors suggest stapling as a strategy for optimizing membrane permeability of cyclic peptides

Cyclic peptides represent a promising class of drug candidates. A significant obstacle limiting their development as therapeutics is the lack of an ability to predict their membrane permeability.

Read