Yeo HC
Metabolomics and modelling approaches for systems metabolic engineering
Metabolic engineering involves the manipulation of microbes to produce desirable compounds through genetic engineering or synthetic biology approaches. Metabolomics involves the quantitation of intracellular and extracellular metabolites, where mass spectrometry and nuclear magnetic resonance based analytical instrumentation are often used. Here, the experimental designs, sample preparations, metabolite quenching and extraction are essential to the quantitative metabolomics workflow.
ReadMachine learning alternative to systems biology should not solely depend on data
Keywords : mechanistic modeling, machine learning, AI, systems biology, synthetic biology, metabolic engineering
Read