Yue W
Computational modelling of flavivirus dynamics: The ins and outs
- Computational methods integrating experimental data help elucidate viral life cycle. - Viruses are dynamic and have complex interactions with a variety of host factors. - We can now model the complex interplay of proteomic and genomic components. - Molecular biology, genomics, and computation complement structural methods.
ReadComputational modelling of flavivirus dynamics: The ins and outs
Enveloped viruses such as the flaviviruses represent a significant burden to human health around the world, with hundreds of millions of people each year affected by dengue alone. In an effort to improve our understanding of the molecular basis for the infective mechanisms of these viruses, extensive computational modelling approaches have been applied to elucidate their conformational dynamics.
Read