Gan SKE
Editorial : A New Home for "Scientific Phone Apps and Mobile Devices" Journal
The original intent of academic publication to disseminate information and findings to the community for scientific progress has taken different twists and turns particularly in the last few decades
ReadThe Associations between Dietary Practices and Dietary Quality, Biological Health Indicators, Perceived Stress, Religiosity, Culture, and Gender in Multi-Cultural Singapore
Dietary quality, biological health, culture, religiosity, and perceived stress are co-related. However, there is a dearth of research conducted on Asian populations in secularized and harmonious multi-cultural societies. This study addresses these gaps by conducting an investigation in the multi-cultural and multi-religious Singapore to examine the parameters of culture and gender and the associations with 1) dietary quality, 2) biological health indicators, 3) religiosity, and perceived stress.
ReadAllosteric Effects between the Antibody Constant and Variable Regions: A Study of IgA Fc Mutations on Antigen Binding
Therapeutic antibodies have shifted the paradigm of disease treatments from small molecules to biologics, especially in cancer therapy. Despite the increasing number of antibody candidates, much remains unknown about the antibody and how its various regions interact. Recent findings showed that the antibody constant region can govern localization effects that are useful in reducing side effects due to systemic circulation by the commonly used IgG isotypes.
ReadRole of FcαR EC2 region in extracellular membrane localization.
The FcαR receptor (CD89) binds to the constant region of Immunoglobulin (Ig) A to mediate mucosal immunity [1–2]. FcαR consist of five exons: two that code for the signal peptide regions S1 & S2, two for the extracellular regions EC1 and EC2, and the final exon for the transmembrane/cytoplasmic tail region [3].
ReadEditorial: The history and future of scientific phone apps and mobile devices
Mobile apps and devices continue to impact our daily lives. In cities all over the world, smartphones have enabled disruptions (including the Internet of Things or IOT) into daily life for good or bad from transport/daily health tracking to indirectly causing accidents from the lack of situational awareness.
ReadEffect of VH–VL Families in Pertuzumab and Trastuzumab Recombinant Production, Her2 and FcγIIA Binding
Many therapeutic antibodies are humanized from animal sources. In the humanization process, complementarity determining region grafting is tedious and highly prone to failure. With seven known VH families, and up to six known κ VL families, there are choices aplenty. However, the functions of these families remain largely enigmatic.
ReadEditorial: APD Trove Journal - scope, aims, and purpose
“Publish or perish” is a mantra that is familiar to all involved in academia. With their careers on the line, publications have become a crucial outlet that most academics have worked towards.
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